Salud Pública de México

Neuropsychological effects among workers exposed to organic solvents

Cuauhtémoc Arturo Juárez-Pérez, Guadalupe Aguilar-Madrid, Jorge Sandoval-Ocaña, Alejandro Cabello-López, Oscar Trujillo-Reyes, Claudia Madrigal-Esquivel, Catharina Wesseling

Resumen


Objective. To assess neuropsychological performance among workers at a paint factory in Mexico City. Materi­als and methods. During 2004 and 2005 we assessed the neuropsychological performance of 208 workers who were exposed to organic solvents at a paint factory, mainly toluene and xylene. We categorized workers into low and high exposure groups using a cumulative index for toluene, based on times spent in different tasks. We evaluated cognitive and motor functions with 13 neuropsychological tests. Results. We found lower attention, longer time to complete the test β=5.5 (R2=12.3%), and a lower score in the motor-cognitive test β=-15.7 (R2=19.5%) in the high exposure group through multiple linear regression model analysis, with adjustment for age and education. Conclusion. Our results are similar to the ones reported in the literature, but the effects are less severe, probably due to lower exposure to organic solvents.


Palabras clave


occupational exposure; solvents; neuropsychological tests

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DOI: http://dx.doi.org/10.21149/9800

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Salud Pública de México es una publicación periódica electrónica, bimestral, publicada por el Instituto Nacional de Salud Pública (con domicilio en Avenida Universidad núm. 655, col. Santa María Ahuacatitlán, Cuernavaca, Morelos, C.P. 62100, teléfono 329-3000, página web, www.insp.mx), con ISSN: 1606-7916 y Reserva de Derechos al Uso Exclusivo con número: 04-2012-071614550600-203, ambos otorgados por el Instituto Nacional del Derecho de Autor. Editor responsable: Carlos Oropeza Abúndez. Responsable de la versión electrónica: Subdirección de Comunicación Científica y Publicaciones, Avenida Universidad núm. 655, planta baja, col. Santa María Ahuacatitlán, Cuernavaca, Morelos, C.P. 62100, teléfono 329 3000. Fecha de última modificación: 11 de abril de 2019. D.R. © por el sitio: Instituto Nacional de Salud Pública.

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